Protein Crystallography and Biophysics Centre (BiophysX)
Institute of Structural and Molecular Biology (ISMB)
Birkbeck College / University College London

Mid- and Far-Infrared Spectroscopy
(Bruker Vertex 80v and IFS/66s)


Vibrational infrared (IR) spectroscopy covers the 4000 to 200 cm-1 (2500 to 50000 nm) spectral range. It is complementary to, and is generally more informative than, UV/visible/near-IR electronic spectra as almost all molecules have characteristic IR spectra. Typical projects include measuring protein and cofactor changes in different intermediates or quantifying specific biochemicals in clinical samples for diagnostics.

These machines can be operated in transmission or ‘ATR’ mode and have DTGS, MCT and helium bolometer detectors. We also have technology to combine IR measurements with electrochemistry, photochemistry and cyclic addition/removal of ligands.

Potential users should firstly contact us to discuss project feasibility and sample requirements, together with likely machine requirements and access charges.

ISMB Protein Crystallography and Biophysics Centre, Birkbeck, University of London
Last modified April 2021