About Us
The Protein
Crystallography and Biophysics Centre (BiophysX)
at ISMB provides access to instrumentation and
expertise for structural biology experiments
covering protein crystallography and several
biophysical methods to members of
ISMB and UCL groups as well as to other
research groups located in London.
Updates
A new VARIOSKAN LUX plate reader has been
installed in the lab. More information about
applications and possibilities please follow the
link on the right.
Refer to Birkbeck web pages or contact us
regarding updated charges for Master's and PhD
students.
Protein Crystallography
BiophysX provides
access to equipment and supplies for
crystallization experiments including initial
screenings, crystal monitoring and
optimization. The Laboratory is also equipped
with an X-ray generator suitable for protein
crystallography data collection. In addition
we are running rolling BAG applications for
access to major synchtrotrons across Europe
covering research groups from Birkbeck, UCL
and QMUL.
Biophysics
A variety of
instrumentation is available for the
characterization of equilibrium and kinetic
behaviors of protein, nucleic acid and
small-molecule interactions on a hire, service or
collaborative basis. For an overview of the
methods and techniques available, please click here.
Planning an experiment
Please read the overview for basic
information and contact the Centre Manager for an
information sheet and questionnaire on a specific
technique. More detailed planning will depend on
the information you return to us. Usual pitfalls
are the solubility or stability of your sample at
the buffer conditions required and the lack of
suitable controls. Thorough data analysis is
essential before conclusions are drawn from any
biophysical experiment. Please discuss this in
advance as well.
Please also note that our
safety regulations need to be followed in
any case..
Access
Currently most of
the biophysics equipment of the previously known
as Biophysics Centre has been moved in room
B16 were is is merged with the existing
Protein Crystallography Laboratory. The new space
offers a wider range of equipment under the same
space as also it is easier accessible for the
external users. Please contact the Centre Manager
if you have any queries.
Bookings for biophysics equipment can be made and
viewed here.
If you have no valid login, please book through
the Centre Manager.
Charges depend on the instrument and on the amount
of training required and service to be provided.
We charge to cover cost and only if there is
sufficient funding on your project. Please
enquire. For future projects involving BiophysX
please contact us well in advance of your grant
application.
Contact and Location
Protein Crystallography and Biophysics Centre Institute of Molecular and Structural Biology Birkbeck, University of London Malet Street London, WC1E 7HX Tel 020 76316458 (from internal: Ext 6458) Email biophysx (at ) mail cryst bbk ac uk
Click
here for maps of the college and
surroundings. Please note some instrumentation is
located nearby at UCL.
Funded by Wellcome
 |
Partner of the MOSBRI
project, funded from
the European Union's Horizon 2020 research
and innovation programme
 |
Centre
Management
Coordination/management: |
Dr. Nikos
Pinotsis
|
Biophysics: |
Dr. Mark A.
Williams |
|
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